Montage of 16 adjacent and overlapping fields of living bone marrow derived macrophages imaged by phase contrast light microscopy. These cells are highly motile. Cells can be viewed interacting over...

Only the macronucleus contains nucleoli which is the site of ribosomal RNA synthesis and ribosome subunit assembly. This EM also contains the distal end of the food vacuole forming cytopharynx which c...

To study the cellular consequences of misfolding of plasma membrane proteins, a transmembrane model protein that was constitutively targeted to the plasma membrane was developed for use as a reporter ...

Time-lapse experiments showing deltorphin II (100 nM; a selective agonist)-induced internalization of delta-opioid receptor–enhanced GFP (DOR-EGFP; green) receptors expressed in HEK 293 cells. The C...

Photoactivation localization microscopy image (PALM) of a human foreskin fibroblast expressing Dronpa-alpha-actinin (red) and tdEos-vinculin (green). This image reveals that although conventional dif...

This total internal reflection (TIRF) image of unconverted tdEos-paxillin (green) and PsCFP20-zyxin (red) demonstrates that these two proteins are almost completely colocalized when observed with diff...

Mouse Embryonic Fibroblasts (MEFs) grown on glass coverslips coated with 10 ug/ml Fibronectin. After 24 hrs cells were fixed in 3% paraformaldehyde and stained with mouse antibody to Paxillin, rabbit...

Parallel stress fibers on the ventral face of an MDCK cell, just inside the plasma membrane. This transmission electron micrograph of a flat-embedded MDCK cell was taken 60-70nm from the interface bet...

Didinium captures Paramecium. A moment after initial contact when toxicysts enter Paramecium. The strand of toxicysts can be seen between the two organisms, and Didinium will use the anchored toxicyst...

Didinium captures Paramecium. The cytostome opens at the end of the proboscis to accept its prey. Also showing metachronous waves of cilia within the two characteristic ciliary girdles of Didinium nas...