Transmission electron micrograph of glutaraldehyde fixed pancreatic acinar cell showing the characteristic features of nuclear chromatin with this preparative method. Darkly staining heterochromatin (here labeled 'chromatin') appears granular and concentrated at the nuclear periphery and nucleolus. Micrograph courtesy of Susumu Ito appears as Figure 118 from Chapter 4 (Nucleus) of 'The Cell, 2nd Ed.' by Don W. Fawcett M.D. A PDF copy of the corresponding chapter is available on the ASCB's BioEDUCATE website.
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