Light microscopy of the same field of cells showing the phase contrast image of a monolayer of K2 Chinese Hamster Ovary (CHO)cells (upper panel), and in the lower panel, immunofluorescence staining using an antibody against a component of the nuclear lamina. Fluorescence is concentrated in the periphery of the nucleus. From Gerace L, Blum, Blobel G (1978) J. Cell Biol. 79, 546-56, reprinted with permission as Figures 159 (upper) and 160 (lower) from Chapter 4 (Nucleus) of 'The Cell, 2nd Ed.' by Don W. Fawcett M.D. A PDF copy of the corresponding chapter is available on the ASCB's BioEDUCATE website.
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