HeLa cells stably expressing BAC-encoded GFP-labeled snRNP protein U1-70K-GFP and imaged witb a Leica SP5 confocal microscope using a 60x 1.4NA HCX Plan Apo objective lens. The U1-70K-GFP is confined to the nucleoplasm and enriched in splicing factor compartments and Cajal Bodies (bright dots). See Fig 1A in Huranova et al. 2010 J Cell Biol 191:75-86.
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