A thinly-spread human skin fibroblast stained by indirect immunofluorescence with actin-specfic antibody. Actin bundles correspond with stress fibers, extending out into the periphery of the cell. Figure 435 from Chapter 16 (Cytoplasmic matrix and cytoskeleton) of 'The Cell, 2nd Ed.' by Don W. Fawcett M.D. Image from Elias Lazarides, J. Cell Biol. 65:549-61, 1975, PMID: 1094020. A PDF copy of the accompanying chapter is available on the ASCB’s BioEDUCATE website.
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