A human skin fibroblast in vitro stained by indirect immunofluorescence with an antibody to tropomyosin. The pattern of tropomyosin staining corresponds with stress fibers and the distribution of polymerized actin. Image from Elias Lazarides, J. Cell Biol. 65:549-61, 1975, PMID: 1094020. Figure 444 from Chapter 16 (Cytoplasmic matrix and cytoskeleton) of 'The Cell, 2nd Ed.' by Don W. Fawcett M.D. A PDF copy of the accompanying chapter is available on the ASCB’s BioEDUCATE website.
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