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*CIL – Cell Image Library accession number. Please use this to reference an image.

CIL:37228*  Cite 
Description

Transmission electron micrograph of a nerve cell synapsing on a dendrite. The synapse contains many synaptic vesicles and a cluster of mitochondria. Note that this very early (1953) micrograph is primarily of historical interest since it pre-dates glutaraldehye fixation which was introduced in the early 60's and is considered essential for adequate nerve tissue preservation. Examples of nerve tissue micrographs prepared in 1965 are CIL:37218, CIL:37219 and CIL:37220. Image made available by James D. Jamieson and the Department of Cell Biology, Yale University School of Medicine.

Technical Details

Original 3.25 in. x 4 in. lantern slides were scanned at 600dpi. Original magnification x35,000.

Biological Sources
Cell Type
neuron
Cellular Component
dendrite
synapse
synaptic vesicle
Biological Context
Biological Process
transmission of nerve impulse
Attribution
Names
Sanford Palay
Link
George E. Palade EM Slide Collection
Citation
Digital Object Identifier (DOI)
doi:10.7295/W9CIL37228
Archival Resource Key (ARK)
ark:/b7295/w9cil37228
Grouping This image is part of a group.
Imaging
Image Type
recorded image
Image Mode
transmission electron microscopy (TEM)
Parameters Imaged
electron density
Source of Contrast
differences in adsorption or binding of stain
Visualization Methods
osmium tetroxide
Processing History
unprocessed raw data
Sample Preparation
Methods
chemically fixed tissue
Relation To Intact Cell
sectioned tissue
Dimensions
Spatial Axis Image Size Pixel Size
X 6000px ——
Y 5162px ——