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Transmission electron micrograph of a polysome (polyribosome) purified from a rat liver homogenate by sucrose gradient centrifugation, and negatively stained with uranyl acetate. The linear arrangement of ribosomes bound to messenger RNA s clearly seen.
Samples were placed on carbon coated collodion films, negatively stained with aqueous uranyl acetate, and examined with a Philips 300 TEM.
See also N. Yoshiaki et al. 1971. Structure of liver ribosomes studied by negative staining. J Mol Biol 60:303-323
- Biological Process
George E. Palade
N. Yoshiaki et al. 1971. Structure of liver ribosomes studied by negative staining. J Mol Biol 60:303-323
George E. Palade EM Slide Collection
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